Detection of Clade 2.3.4.4b Avian Influenza A(H5N8) Virus in Cambodia, 2021Article Published on 2023-01-012023-06-14 Journal: Emerging Infectious Diseases [Category] Fulltext, 조류인플루엔자, [키워드] Avian influenza virus Cambodia Disease surveillance food safety H5N8 Influenza Live poultry markets pathogenic phylogenetics respiratory infections viruses whole-genome sequencing zoonoses. [DOI] 10.3201/eid2901.220934 PMC 바로가기
SARS-CoV-2 shedding dynamics and transmission in immunosuppressed patients면역 억제 환자의 SARS-CoV-2 발산 역학 및 전파Article Published on 2022-12-012022-09-11 Journal: Virulence [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus adjust analysed anatomic site characterized collected conducted coronavirus Diagnosis Diversity dominant E484K first positive fitness genetic change Genome genomic Host hosts household transmission Immunosuppressed immunosuppressed patient immunosuppressed patients in urine in vivo Infection Interaction knowledge long-term viral shedding mother mutate Mutation mutation dynamics N501Y occurred P681R Patient replicate residue residues SARS-CoV-2 SARS-CoV-2 evolution selective Sequencing severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specific treatment Spike protein spread to Substitution temporal dynamics Transmission two patients Urine variant variant of concern variants variants of concern virus whole genome Whole genome sequencing whole genome sequencing. whole-genome sequencing [DOI] 10.1080/21505594.2022.2101198 PMC 바로가기 [Article Type] Article
Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics InitiativeArticle Published on 2022-11-032022-11-15 Journal: PLoS Genetics [Category] SARS, 변종, 진단, [키워드] analysis Analysis association chromosome Cohort controls country COVID-19 Deleterious disease expected Genetic genetics Genome-wide association study identify increase in initiative loci outcome outcomes Pathogenesis performed rare variant Result severe disease Support susceptibility the SARS-CoV-2 TLR7 Toll-like receptor variant whole-genome sequencing with COVID-19 [DOI] 10.1371/journal.pgen.1010367 PMC 바로가기
Antibody response and intra-host viral evolution after plasma therapy in COVID-19 patients pre-exposed or not to B-cell-depleting agentsArticle Published on 2022-11-012022-11-15 Journal: British Journal of Haematology [Category] SARS, 진단, [키워드] anti-CD20 anti-CD20 therapy Anti-spike anti-Spike IgG antibody antibody kinetics B-cell clinical care clinical status clinical symptom Complete contribute convalescent convalescent plasma COVID-19 patient Decline donors eligible evaluated Follow-up hospitalized COVID-19 patients humoral Humoral immunity IgG Immune escape Immunocompromised Immunocompromised patients Immunoglobulin impair lymphopenia majority management mRNA-based vaccine mRNA-based vaccine plasma mutation rate Patient patients treated plasma receiving SARS-CoV-2 SARS-CoV-2 viral load SARS-CoV-2-specific antibodies severity spike mutations survival therapy titre viral control viral evolution virus clearance WHO whole-genome sequencing Whole-genome sequencing. World Health Organization [DOI] 10.1111/bjh.18450 PMC 바로가기
A Robust, Highly Multiplexed Mass Spectrometry Assay to Identify SARS-CoV-2 VariantsArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome Care characterized circulation Clinical studies collected coronavirus defined Delta demonstrated diagnostic diagnostic capability effort functional health system health systems identify increasingly Infection prevention Iota Laboratory MALDI-TOF mass molecular MOST multiplex New York City omicron Panel Patient Patient care polymorphism Population public health measures public health systems RNA robust RT-PCR SARS-CoV-2 SARS-CoV-2 lineage SARS-CoV-2 variant seeking sensitivity specificity specimen Spectrometry Surveillance target tested Transmissibility USA utility vaccination variant variant call variant panel. virus WGS while whole-genome sequencing [DOI] 10.1128/spectrum.01736-22 PMC 바로가기
Detection and prevalence of SARS-CoV-2 co-infections during the Omicron variant circulation in FranceArticle Published on 2022-10-232022-11-15 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Admission bioinformatics circulation clinical impact Co-infection collected Delta detect detection evaluate evaluated France genetic diversity genomic hospitalized patients ICU intensive care isolate Lineage lineages omicron Patient patients Prevalence question raised random recombinants reported risk SARS-CoV-2 SARS-CoV-2 variant sets of primer Surveillance variant whole-genome sequencing [DOI] 10.1038/s41467-022-33910-9 PMC 바로가기
SARS-CoV-2 variants of concern and spike protein mutational dynamics in a Swedish cohort during 2021, studied by Nanopore sequencingArticle Published on 2022-10-182022-11-15 Journal: Virology Journal [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] A222V analysed approach ARTIC Network assist bioinformatics can be used circulating variant Cohort COVID-19 COVID-19 pandemic Delta delta variant distribution genomic Health include less mapped Mutation mutations nanopore sequencing National occurred omicron Patient positive primer Protein public health public health measures Q677H S protein SARS-CoV-2 SARS-CoV-2 genomes SARS-CoV-2 variant sequence Sequencing sequencing method spike Spike protein Surveillance Swedish the S protein the SARS-CoV-2 the Spike Uppsala County variant variants variants of concern. variants of interest VoC whole-genome sequencing [DOI] 10.1186/s12985-022-01896-x PMC 바로가기
Genomic diversity of SARS-CoV-2 in Pakistan during the fourth wave of pandemic전염병의 네 번째 물결 동안 파키스탄에서 SARS-CoV-2의 게놈 다양성Article Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] A222V acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected Alpha B.1.617.2 Beta variant characteristic circulating circulation conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 D950N delta variant Delta variants exhibited followed by G142D genomic Genomic surveillance Germany globe highlight Illumina isolate isolates Karachi L452R lineages P681R Pakistan pandemic Patient Phylogenetic analysis SARS-CoV-2 SARS-CoV-2 strain severe acute respiratory syndrome Coronavirus Singapore spike mutation T19R T478K United Kingdom V483A variant variants variants of concern variants of concern. whole-genome sequencing [DOI] 10.1002/jmv.27957 PMC 바로가기 [Article Type] Article
Rapid transition between SARS-CoV-2 variants of concern Delta and Omicron detected by monitoring municipal wastewater from three Canadian cities캐나다 3개 도시의 도시 폐수를 모니터링하여 SARS-CoV-2 변종 우려 델타와 오마이크론 간의 신속한 전환 감지Article Published on 2022-10-012022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Affect BA.1 BA.2 biases Chemical Chemical tracer collected Concentration correlation Delta demography determined by dominant Factor Government greater incidence of COVID-19 individuals introduced Lineage lineages local outbreak local outbreaks Migration MONITOR monitoring omicron pandemic plant Population Population size Prairie predominant proportion qPCR Rapid Raw influent Regulation RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 variant Surveillance surveillance data Treatment variant Variant of concerns variants variants of concern viral loads VoC VOCs was used wastewater Wastewater. whole-genome sequencing [DOI] 10.1016/j.scitotenv.2022.156741 PMC 바로가기 [Article Type] Article
Unexpected details regarding nosocomial transmission revealed by whole-genome sequencing of severe acute respiratory coronavirus virus 2 (SARS-CoV-2)Article Published on 2022-10-012022-11-16 Journal: Infection Control and Hospital Epidemiology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] age analysis Analysis clade Clinical characteristics cohort study collected coronavirus disease COVID-19 Deceased died epidemiological epidemiological data evaluate event Genetic HCW HCWs healthcare worker hospital identify indicated Infection prevention knowledge male measure Measures mechanism median medical records nasopharyngeal sample nosocomial nosocomial COVID-19 Nosocomial infection NPs outbreak outcome Patient patients performed Phylogenetic analysis positive provided Respiratory Coronavirus RNA SARS-CoV-2 selected significantly higher subclade supported Transmission viral clade virus WGS whole-genome sequencing [DOI] 10.1017/ice.2021.374 PMC 바로가기